Saint Bonaventure beats Niagara 71-52
Powerful weight-loss drugs are expanding use of U.S. health care as patients starting prescriptions are diagnosed with obesity-related conditions or take the drugs to become eligible for other services, health records and discussions with doctors show. An exclusive analysis of hundreds of thousands of electronic patient records by health data firm Truveta found slight, but measurable, increases in first-time diagnoses of sleep apnea, cardiovascular disease, and type 2 diabetes within 15 days of an initial prescription for a GLP-1 weight-loss drug between 2020 and 2024. In addition to obesity-related conditions, some patients are being prescribed the drugs to lose weight and become eligible for services, including organ transplants, fertility treatments or knee replacements, according to interviews with seven doctors and five other health experts. "This is a population that previously felt stigmatized by health care providers and often didn't return. But now that they're actually seeing themselves get healthier, asking clinicians questions and engaging more, I do think we're seeing new patients," said Dr. Rekha Kumar, a New York endocrinologist and obesity medicine specialist. Novo Nordisk's Wegovy and Ozempic and Eli Lilly's Zepbound and Mounjaro have been shown to lead to average weight loss of at least 15%. Andrew Friedson, director of health economics at the Milken Institute and three other experts said the impact of the drugs on overall healthcare use is not yet clear. The new diagnoses could mean higher initial spending, but early detection could save costs down the line, he said. Dr. Courtney Younglove, an obesity medicine specialist and founder of Heartland Weight Loss clinic in Overland Park, Kansas, said she has referred obesity patients for long-delayed pap smears and other routine care, including colonoscopies. Many overweight patients avoid doctors and routine tests for years due to the stigma and bias they often encounter, she said. “A lot of people with obesity don't do a lot of preventive health maintenance." Phil, a 43-year-old Chicago technology executive who asked for his full name to be withheld for privacy reasons, generally avoided doctors before receiving a GLP-1 prescription from a telehealth provider in early 2023. He said he told his regular physician about the medication months later, after he had lost more than 30 lbs, and was taken aback by her supportive response. He decided then to advocate more for himself and ask for help with other conditions, including addiction and mental health. "It gave me the courage to ask," he said. The Truveta analysis found that for every 1,000 patients with a first-time GLP-1 prescription, 42 were diagnosed with type 2 diabetes within 15 days in 2024, up from 32 in 2020. Over the same period, the number of sleep apnea diagnoses per 1,000 patients rose to 11 from 8 and the number of cardiovascular disease diagnoses increased to 15 from 13. The most obese patients were twice as likely as people who were less overweight to receive a type 2 diabetes diagnosis, and three times as likely to be diagnosed with sleep apnea, the Truveta data showed. The analysis was based on 33,630 first-time GLP-1 prescriptions for overweight or obese patients in 2020 and 224,496 in the first 10 months of 2024. Lilly declined to directly comment on the data, saying in an emailed statement "it is important that adults living with obesity receive appropriate diagnosis and access to evidence-based care." Novo Nordisk also declined to comment directly, noting its aim "to address unmet needs for a wider range of patients." QUALIFYING FOR SURGERIES ResMed, which sells sleep apnea devices, had revenue growth of 11% for its fiscal year ending in June - a trend the company attributed in part to the GLP-1 drugs. The medications are "bringing people into primary care like never before," ResMed CEO Michael Farrell said at the company's recent shareholder meeting. In addition to things like sleep apnea, the weight-loss drugs could lead to more joint replacements, said Sara Mallatt, director of healthcare research at market analysis firm AlphaSense. "As people's BMIs come down, they'll be eligible for surgeries they wouldn't otherwise," she said. "No one is saying this is happening in a meaningful way right now, but we think it will." University of Chicago Medicine last year launched a weight-loss clinic aimed at helping prospective organ transplant patients lose weight to qualify for surgery, with the GLP-1 drugs playing a key role. "Before they had a place to send these patients, which is our clinic, the scheduler would just say, 'hey, what's your weight, what's your height, what's your BMI,' and if they didn't fit their criteria, they would just tell them to lose weight on their own," said Anesia Reticker, the center's clinical pharmacist specialist. Retired Indiana steelworker Bensabio Guajardo, 68, was prescribed Ozempic at the clinic in 2023 when he was deemed too obese for a double lung transplant needed to keep him alive after pulmonary fibrosis made breathing increasingly difficult. "It helped me a lot. It took my cravings away," Guajardo said. After losing around 90 pounds and stopping the drug ahead of a successful surgery in May, his doctor put him back on it to control high blood sugar. Reticker said the program has received about 100 referrals over the past year from transplant centers in the Chicago area.PTI convoys enter Federal Capital as dialogue hits snags
Adele has opened up about how her two-year Las Vegas residency got off to a "rocky" start. or signup to continue reading The Chasing Pavements singer, 36, mounted the gigs after a traumatic time in 2022 which saw her cancel the shows less than a day before the first one was set to kick off – and wrapped them up on Saturday night with an emotional performance at Caesars Palace that saw her kiss her 12-year-old son Angelo and fiancée Rich Paul, 43, after making a speech to fans about her battle to put them on. She told the crowd in a video shared on social media: "I am so sad that this residency is over and I am so glad that it happened – I really, really am. "It got off to such a f****** rocky, rocky way. It was one of the worst years of my life. "I was being punched around, it was horrible and I was told it was career suicide and Vegas would never forgive me for (cancelling) so last minute." Ahead of her last show on Saturday, Adele told how she was looking forward to enjoying red wine and resting in bed. She told fans at one of her recent shows in Sin City, she said: "Doing four hours a weekend of completely live singing is a lot. "And I chat a lot, and I'm very, very sensitive and I'm emotional. I am battered after these shows. And I take every single person on in this room into my soul, I take you home with me. She added she's been on "full recovery" between shows and was ready for them to be over. Adele went on: "It's a big deal to me because it's very, very bittersweet. But (my residency) has been in my mind for four years... four years for one f****** idea. "So I'm looking forward to having loads of spare time to love on my kids, to love on my man and to love on another kid. To love on my house. "Saturday night (when the residency ends), I'm probably going to have a (lot) of red wine. "So that's the most exciting thing for when the show ends! Then after that I think I'm just going to really, really veg until the end of the year. I feel like I'm early hibernating already." Advertisement Sign up for our newsletter to stay up to date. We care about the protection of your data. Read our . AdvertisementKobe Sanders tied a season high with 27 points as Nevada claimed fifth place in the Charleston Classic with a 90-78 victory over Oklahoma State Sunday afternoon in South Carolina. Sanders helped the Wolfpack (6-1) earn a second win following one-possession games against Vanderbilt and VCU. After hitting the decisive 3-pointer with five seconds left in Friday's 64-61 win over VCU, Sanders made 7 of 10 shots, hit three 3s and sank 10 of 13 free throws Sunday. Javascript is required for you to be able to read premium content. Please enable it in your browser settings. Peggy Slappey Properties and Vision Home Crafters invite you to Old Town Estates, where easy country living meets the convenience of great local amenities and top-rated schools. These elegant single-family homes are situated on large lots (up to four acres) and showcase open floor plans, spa... Click for more. ON THE MARKET: Escape the City at Old Town Estates in MonroeINDIANAPOLIS (AP) — The Indianapolis Colts defense started this season struggling. It couldn't stop the run, couldn't keep teams out of the end zone, couldn't get off the field. Now the script has flipped. Defensive coordinator Gus Bradley's group is playing stouter, holding teams — even the high-scoring Detroit Lions — largely in check long enough to give Indy a chance to win, and it's the Colts offense that has struggled. “They are playing their tails off. You don’t want them on the field a bunch and as an offense you want to be able to play complementary football,” running back Jonathan Taylor said after Sunday's 24-6 loss. “I would say specifically on offense, it sucks when you can’t help your defense out when they are fighting their tails off all game.” Indy's defense held up its end of the bargain by limiting the Lions (10-1) to 14 first-half points and allowing just 24, matching Detroit's lowest output since Week 3. The problem: Even when the Colts (5-7) did get Detroit off the field, they couldn't sustain drives or score touchdowns. Again. Anthony Richardson provided the bulk of the ground game by rushing 10 times for 61 yards, mostly early. Taylor managed just 35 yards on 11 carries and a season-high 10 penalties constantly forced the Colts to dig out from deep deficits. Part of that was by design. “We knew Jonathan Taylor was going to be the guy we needed to shut down,” Lions coach Dan Campbell said. “We did that. The quarterback runs. It got us on a couple but overall, we did what we needed to do, and we kept them out of that game." Part of it could be because of an injury-battered offensive line that has started three rookies each of the past two weeks and finished the previous game with the same three rookies. Whatever the fix, Indy needs a good solution. There is good news for Indy is that its schedule now gets substantially more manageable. After losing four of five, all to teams in playoff position and three to division leaders, Indy faces only one team with a winning record in its final five games. The most recent time the Colts played a team with a losing mark, Richardson rallied them past the New York Jets 28-27. But Colts coach Shane Steichen knows that's not the answer. The Colts must get this offense righted now. “We’ve got to get that figured out. We’ve got to get him going on the ground,” Steichen said when asked about Taylor, who has 92 yards on his past 35 carries. “We’ll look at the offensive line. We’ll look at everything." What’s working Pass rush. Pro Bowl DT DeForest Buckner's presence certainly has been felt since he returned from a sprained ankle Oct. 27. In those past five games, the Colts have had 14 sacks, including three of Jared Goff on Sunday. What needs work Penalties. The Colts have had one of the cleanest operations in the league most of this season. Sunday was an anomaly, but one that can't merely be written off. Stock up WR Michael Pittman Jr. The five-year veteran is one of the league's toughest guys, but playing through a back injury appeared to take its toll on Pittman's productivity. Since sitting out in Week 10, Pittman has 11 receptions for 142 yards including six for 96 yards, his second-highest total of the season, Sunday. Stock down Tight ends. Each week the Colts want their tight ends to make an impact. And each week, they seem to fail. It happened again Sunday when Drew Ogletree dropped a TD pass that would have given Indy a 10-7 lead. Instead, Indy settled for a field goal and a 7-6 deficit. Through 12 games, Indy's tight ends have a total of 26 catches, 299 yards and two TDs. That's just not good enough in a league where versatile, productive tight ends increasingly signal success. Injuries Pittman and WR Josh Downs both returned to the game after leaving briefly with shoulder injuries. WR Ashton Dulin did not return after hurting his foot in the second half. But the bigger questions come on the offensive line. LT Bernhard Raimann (knee) was inactive Sunday, and rookie center Tanor Bortolini entered the concussion protocol Monday. Bortolini was one of three rookie starters the past two weeks, replacing Pro Bowler Ryan Kelly who is on injured reserve. Key number 55.88 — Indy has scored touchdowns on 55.88% of its red zone trips this season. While it puts it near the middle of the NFL, it's cost the Colts multiple wins. Next steps Richardson needs to rebound from this latest 11 of 28 performance and show he can lead the Colts to victories week after week. He'll get plenty of chances over the season's final month, starting with next week's game at the New England Patriots. AP NFL: https://apnews.com/hub/nfl
Saint Bonaventure beats Niagara 71-52
A role reversal doomed the No. 22 Xavier Musketeers in their only loss of the season, against Michigan at the Fort Myers Tip-Off on Wednesday. Normally a team that avoids committing turnovers and pressures its opponent into making them, Xavier (6-1) will try to recapture its early-season winning form when it hosts South Carolina State on Sunday in Cincinnati. Through their six wins, the Musketeers had just 58 turnovers while forcing 82 by their opponents. But against the Wolverines, they lost the turnover battle 19-10 and the game 78-53. The Musketeers committed 14 turnovers in the first half and fell behind 41-30. Xavier head coach Sean Miller credited his team for typically playing an up-tempo style while avoiding mistakes, while also acknowledging that the turnover bug really bit them against the Wolverines. "We lost to a really good team; no shame in that," Miller said. "We, on top of that, didn't play well." "And that (avoiding turnovers) is something you (usually) do well? That's going to be hard to overcome against a quality team like Michigan." Leading scorer Ryan Conwell (17.6 points per game) gave the Musketeers a boost with 19 points. Zach Freemantle, second on the team at 15.4 ppg, added 14 points and 10 rebounds. Problematically, however, they also contributed to the turnover problem with three apiece. "We didn't play well enough to win the game," Miller said. "The game got out of hand. It's not like our guys quit. Their depth just continued to wear on us." The Musketeers also get 11 points and a team-high 4.4 assists per game from Dayvion McKnight. The guard had just one turnover against Michigan, but he also made just one of his eight shot attempts. Xavier may have an opportunity get right in the turnover area against the Bulldogs (4-4), who are No. 207 in the NCAA in assist-to-turnover ratio at 1.11. South Carolina State is fresh off an 82-53 road loss to Marshall on Wednesday, in a game in which turnovers weren't a huge problem. But assists and made shots were hard to come by for the Bulldogs. Leading scorer Drayton Jones (12.0 ppg) again paced his team in points with 10 vs. Marshall, but the Bulldogs as a team managed just six assists and shot terribly at the 3-point (18.8 percent) and the free-throw (47.1 percent) lines. Jones is also the team's leading rebounder with 5.1 a game, but no Bulldogs player is averaging more than two assists. It's all part of the learning process for coach Erik Martin, whose first team went 5-26 in 2022-23. The Bulldogs improved to 14-18 last season, including 9-5 in the Mid-Eastern Athletic Conference. "The only way you can grow sometimes is by failure or by struggling," Martin said this offseason. "You have to fail in order to learn how to deal with failure and move on and become the person you're supposed to be." --Field Level Media